POWDER MIXING – IMPACT OF PROCESS PARAMETERS ON MIXING
In this case study, SmartDEM is used to study the blending of dissimilar powders in a mixer. DEM model was used to understand the effect of process variables and fill levels on process KPPs. Transient effects could be studied as well.
POWDER MIXING – Screw Conveyor – IMPACT OF PROCESS PARAMETERS ON MIXING
In this case study, SmartDEM was used for blending of dissimilar powders in a mixer. Powders with different PSDs mixed in a continuous blender. Uniformity of composition is a key performance parameter (KPP) for the mixing process amongst others. DEM model was used to understand the effect of process variables (properties of flow can be changed in different bins to reflect process effects, eg. cooking). Transient effects could be studied as well.
DIE-FILLING FOR TABLETING – EVALUATION OF FILL STRATEGIES
Die filling is a continuous periodic procedure where dry or cohesive powders are filled in small hollow cavities (die) usually assisted by air-flow. The speed of carousel (rotation rate), fluid flow properties (punch speed), material flow properties, feed frame paddle speed and feed rate affect the process.
REACTING FLOW OF GRANULAR MATERIAL – MULTISCALE/MULTIPHYSICS ANALYSIS FOR PROCESS OPTIMIZATION
Modeling framework involved a combination of population balance modeling, Discrete Element Modeling (DEM) and flowsheet modeling.